Clean-in-Place (CIP) & Steam-in-Place (SIP) Solutions
CIP and SIP solutions and systems reliably clean equipment with processes that optimize chemical use and minimize cleaning time for limited disruption.
CIP and SIP solutions and systems reliably clean equipment with processes that optimize chemical use and minimize cleaning time for limited disruption.
Ensuring the efficacy of CIP/SIP processes for a biomanufacturing facility requires precise measurement and control. Without the right systems in place, managing the sequencing of lines and vessels for cleaning while optimizing production can become a scheduling challenge. Emerson’s process equipment and control systems provide a lower-cost, regulatory-compliant solution that increases efficiency, improves safety by reducing cross-contamination, and offers greater assurance of product quality.
Effective sterilization of a facility’s lines and vessels is largely dependent on CIP/SIP processes reaching and maintaining specific temperatures. Deviations in temperature or inaccurate readings from faulty equipment can diminish the efficacy of these processes and lead to contamination that results in loss of product. Emerson’s comprehensive set of temperature management technologies ensures accurate, repeatable temperature measurements with robust equipment that withstands harsh conditions.
ASCO Solenoid Valves
World’s largest selection of 2-way, 3-way and 4-way solenoid valves, designed to handle demanding fluid control applications.
DeltaV Distributed Control System
Emerson combines ease of use, full-scale control capabilities, and powerful system integration to deliver a reliable DCS offering that simplifies complex operations and increases productivity.
Electronic Batch Record Management
Reduce release cycle time, while improving the accuracy and consistency of your batch records.
Rosemount™ 68Q Sanitary Temperature Sensor
This sensor is engineered to provide flexible and reliable temperature measurements in hygienic process environments for the food and beverage, pharmaceutical and life-science industries.
Rosemount™ 644 Temperature Transmitter
Engineered for versatility, the Rosemount 644 Temperature Transmitter is available with HART®, FOUNDATION™ Fieldbus or PROFIBUS® protocols in head, field or rail mount styles and a variety of enclosure options.
Rosemount X-well™ Technology
Emerson’s temperature measurement products provide innovative solutions for your most challenging applications.
Precise control of pressure during steam-in-place procedures ensures efficacy by achieving saturated steam supplies as well as minimizing pressure differential across filters so that filter integrity is maintained. Emerson’s wide array of innovative and robust pressure-management solutions provide enhanced sensing, measurement and control capabilities while meeting tough process requirements to reduce cross-contamination, assure compliance with regulations and keep personnel safe.
ASCO Solenoid Valves
World’s largest selection of 2-way, 3-way and 4-way solenoid valves, designed to handle demanding fluid control applications.
DeltaV Distributed Control System
Emerson combines ease of use, full-scale control capabilities, and powerful system integration to deliver a reliable DCS offering that simplifies complex operations and increases productivity.
Electronic Batch Record Management
Reduce release cycle time, while improving the accuracy and consistency of your batch records.
Rosemount™ Wireless Pressure Gauge
This pressure sensor provides up to 10 years of maintenance-free operation and replaces mechanical components for more reliable readings and a higher overpressure limit.
Rosemount™ 3051HT Hygienic Pressure Transmitter
The Rosemount 3051HT Hygienic Pressure Transmitter is a best-in-class transmitter solution for gage and absolute measurements in the pharmaceutical and food and beverage industries.
Automatic, reproducible and reliable delivery of cleaning solutions and rinse water through process equipment and piping requires precise, accurate flow control. An inability to maintain established flow rates necessary for cleaning can result in bacterial growth and cross-batch contamination. Emerson’s portfolio of flow control solutions maintains and validates flow rates for clean-in-place processes to ensure effective cleaning of process equipment and regulatory compliance.
Asset Management Software
Improve maintenance efficiency with real-time predictive diagnostics from your intelligent field devices.
DeltaV Distributed Control System
Emerson combines ease of use, full-scale control capabilities, and powerful system integration to deliver a reliable DCS offering that simplifies complex operations and increases productivity.
Syncade Electronic Batch Records Management
Syncade's Electronic Batch Records, designed for the Life Sciences industry, helps manufacturers ensure product quality and safety through material identification and verification, guaranteeing product potency and purity is delivered right first time.
Micro Motion H-Series Hygienic Coriolis Flow and Density Meters
Ideal for hygienic process-control applications, H-Series flow meters are accurate, low frequency, fit-and-forget meters with a compact, drainable, cleanable design.
Micro Motion D-Series Coriolis Flow Meters
Model D flow meters provide flow and density measurements for specialized applications including hygienic, corrosive and high pressure.
Micro Motion ELITE Peak Performance Coriolis Flow and Density Meter
With unmatched flow and density measurement for liquids, gases and multiphase flow, ELITE Coriolis flow meters deliver in the the most challenging environments and applications.
Fittings, Connectors, Couplings
Motor Starters
Enclosures and Junction Boxes
Ensuring effective sanitation and sterilization is a complex process. Creation and distribution of required acid and caustic solutions, water and steam along with coordination of appropriate segment CIP/SIP cycles can be challenging. Emerson’s distributed control systems allow CIP/SIP demand to be integrated into a plant’s control system strategy, and its manufacturing execution systems enable electronic record-keeping such as configuration methods and calibration events to ensure compliance.
Syncade Equipment Management
Syncade Equipment Management allows you to take your paper-based equipment log books online.
Electronic Batch Record Management
Reduce release cycle time, while improving the accuracy and consistency of your batch records.
ASCO Solenoid Valves
World’s largest selection of 2-way, 3-way and 4-way solenoid valves, designed to handle demanding fluid control applications.
Frequently Asked Questions about Clean-in-Place Steam-in-Place
CLEAN IN PLACE
The process for cleaning production facilities (tanks, pipes, machines) without dismounting by means of a parallel water (and cleaning agents) circuit. To guarantee compliance with hygienic standards in food and beverage, pharmaceutical and cosmetic industries, the cleaning process uses different cycles with washing and rising agents which could be automatically controlled by an automatic programmer. This cleaning in place is launched immediately after production to avoid a contamination and the proliferation of bacteria.
STEAM (STERILIZATION) IN PLACE
For some of the processes, Clean In Place is not enough, and sterilization is required to destroy all microbial germs in the installation by adding a cycle with steam (and disinfectants) after the clean in place phase.
The food and beverage as well as the pharmaceuticals industries frequently use CIP and SIP because cleaning is imperative. Manual cleaning and the cost of down time would not have optimal ROI – therefore CIP and SIP was the obvious solution. CIP and SIP allow the cleaning and the sterilization of the piping and process equipment without having to dismount them.
Manual cleaning lacks consistency and manual monitoring and reporting is prone to human errors. Clean in place cycles can also consume significant amounts of media and energy and any unplanned downtime can directly impact production. Emerson is continuously improving their expertise and efficiency with CIP and SIP. Whether the user needs more effective decision making with analysis and visualization, insights into mobility tools, information and prescribed actions or even help seeing measurable inputs in temperature, flow or position, Emerson can help.
The CIP reports completion in three ways. First, the operator station will have an alert. Second, a text message can be sent to plant personnel. Finally, a comprehensive report can be emailed to key personnel anywhere within the organization.
At a minimum, sensors required are conductivity or pH, flow rate and temperature. To optimize the system, we would suggest level measurement for the chemical and recovery tanks, differential pressure across filters, fluid density.
Clean-in-place (CIP) processes are vital to operations, but they can also be a major source of inefficiencies. Josh Friesz discusses CIP optimization and how conductivity sensors can help you manage the transition between steps in your CIP program.
Clean-in-place or steam-in-place cycle is critical for maintaining sanitary food and beverage and pharmaceutical operations. @Josh Friesz discusses a hygienic pressure transmitter solution for CIP/SIP with improved batch-to-batch repeatability.
A best practice tutorial that demonstrates to users in pharmaceutical and food and beverage industries how effective conductivity measurement in CIP operations can help save time and costs, reduce water and chemical usage, and mitigate risk to product quality and consumer safety.
Selecting the correct instrumentation can help to optimize your CIP process and reduce overall operating costs. In this presentation we will discuss common CIP efficiency challenges and discuss the proper instrumentation to overcome these challenges.
The ASCO Series 273 & 373 Pneumatic Pinch Valve offers high performance, reliability, faster setup, operational flexibility and reduced maintenance cycles
A complete point solution for process temperature measurement that does not require a thermowell or process penetration. Safely record accurate temperature measurements and eliminate the need for cutting pipes, wake frequency calculations or process shutdown.
Clean-in-place (CIP) processes are vital to operations, but they can also be a major source of inefficiencies. Josh Friesz discusses CIP optimization and how conductivity sensors can help you manage the transition between steps in your CIP program.
Clean-in-place or steam-in-place cycle is critical for maintaining sanitary food and beverage and pharmaceutical operations. @Josh Friesz discusses a hygienic pressure transmitter solution for CIP/SIP with improved batch-to-batch repeatability.
A best practice tutorial that demonstrates to users in pharmaceutical and food and beverage industries how effective conductivity measurement in CIP operations can help save time and costs, reduce water and chemical usage, and mitigate risk to product quality and consumer safety.
Selecting the correct instrumentation can help to optimize your CIP process and reduce overall operating costs. In this presentation we will discuss common CIP efficiency challenges and discuss the proper instrumentation to overcome these challenges.
The ASCO Series 273 & 373 Pneumatic Pinch Valve offers high performance, reliability, faster setup, operational flexibility and reduced maintenance cycles
A complete point solution for process temperature measurement that does not require a thermowell or process penetration. Safely record accurate temperature measurements and eliminate the need for cutting pipes, wake frequency calculations or process shutdown.
